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Publications

Scientific Publications

Diabetes, Obesity and Metabolism |  June 28, 2023

First-in-human study of a pharmacological duodenal exclusion therapy shows reduced postprandial glucose and insulin and increased bile acid and gut hormone concentrations

Scientific Presentations

American Diabetes Association (ADA) 84th Scientific Sessions | June 21-24, 2024

GLY-200 (Oral Pharmacologic Duodenal Exclusion Drug) Reduces Glucose and Bodyweight in Patients with Type 2 Diabetes

American Diabetes Association (ADA) 84th Scientific Sessions | June 21-24, 2024

GLY-200 (Oral Pharmacologic Duodenal Exclusion Drug) Decreases Appetite, Increases Satiation, and Reduces Food Intake in Patients with Type 2 Diabetes

American Diabetes Association (ADA) 84th Scientific Sessions | June 21-24, 2024

GLY-200 (Oral Pharmacologic Duodenal Exclusion Drug) Improves Glycemic Control as Measured by CGM in Patients with Type 2 Diabetes

ObesityWeek 41st Annual Meeting of the Obesity Society | October 14-17, 2023

GLY-200 (Oral Pharmacologic Duodenal Exclusion) Reduces Bodyweight and Glucose in Patients with T2D

ObesityWeek 41st Annual Meeting of the Obesity Society | October 14-17, 2023

Intestinal Mucus Complexation by an Oral Duodenal Exclusion Treatment for T2DM and Obesity

ObesityWeek 41st Annual Meeting of the Obesity Society | October 14-17, 2023

GLY-200 (Oral Pharmacologic Duodenal Exclusion) Reduces Appetite and Food Intake in Patients with T2D

American Diabetes Association (ADA) 83rd Scientific Sessions | June 23-26, 2023

First-in-Human Study of a Pharmacological Duodenal Exclusion Therapy Mimics a Roux-en-Y Gastric Bypass Biomarker Signature

American Diabetes Association (ADA) 83rd Scientific Sessions | June 23-26, 2023

Duodenal Targeting by Oral Pharmacologic Duodenal Exclusion Therapy for Treatment of Type 2 Diabetes (T2D)

American Diabetes Association (ADA) 83rd Scientific Sessions | June 23-26, 2023

Coadministration of Metformin with GLY-200, a Clinical-Stage Nonabsorbed Drug for the Treatment of Type 2 Diabetes (T2D), Has No Significant Impact on the Oral Absorption of Metformin in the Rat

American Diabetes Association (ADA) 83rd Scientific Sessions | June 23-26, 2023

GLY-200, a Pharmacologic Duodenal Exclusion Therapy, Improved Metabolic Parameters in the DIO Rat

Polymers in Medicine and Biology | Nov 28-Dec 1, 2022

GLY-200: A novel polymer therapeutic for metabolic diseases

6th Obesity and Nash Drug Development Summit | Nov 29-Dec 1, 2022

Forging Success in Type 2 Diabetes: Treatment & Reversal of T2D & Interrogating Cross-Talk in Metabolic Syndrome

ObesityWeek 40th Annual Meeting of the Obesity Society | Nov 1-4, 2022

A First-in-Human Study of GLY-200, an Oral, Gut-Restricted, Pharmacologic Duodenal Exclusion Therapy

European Association for the Study of Diabetes (EASD) 58th Annual Meeting | Sep 20-23, 2022

Validation of duodenal targeting by oral pharmacologic duodenal exclusion therapy for treatment of type 2 diabetes

American Diabetes Association (ADA) 82nd Scientific Sessions | June 3-7, 2022

Chronic Oral Polymeric Duodenal Exclusion Therapy Has Profound Metabolic Benefits in a T2D Rat Model and Affects Duodenal Morphological Enteroplasticity Similar to RYGB surgery: Implications for T2D Therapy

ObesityWeek 39th Annual Meeting of the Obesity Society | Nov 1-5, 2021

Significant Weight Loss Due to a Novel Oral Polymeric Mucin Binding Duodenal Exclusion Therapy

European Association for the Study of Diabetes (EASD) 57th Annual Meeting | Sep 27-Oct 1, 2021

Robust metabolic benefits of a novel orally administered polymeric duodenal exclusion therapy in animal models of type 2 diabetes: an alternative treatment for type 2 diabetes

American Diabetes Association (ADA) 81st Scientific Sessions | June 25-29, 2021

Profound Metabolic Benefits Observed in an Eight-Week GK Rat Study of a Novel Orally Administered Polymeric Duodenal Exclusion Therapy: Implications for Type 2 Diabetes (T2D) Therapy

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